Thermo Fisher Scientific MTHFR Monoclonal Antibody (5D3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:1,000

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human, Rat

Published species

Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

5D3

Immunogen

Purified recombinant fragment of human MTHFR expressed in E. Coli.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.03% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_11154428

Product Specific Information

MA5-15844 targets MTHFR in indirect ELISA, IHC and WB applications and shows reactivity with Human and Rat samples.

The MA5-15844 immunogen is purified recombinant fragment of human MTHFR expressed in E. Coli. .

MA5-15844 detects MTHFR which has a predicted molecular weight of approximately 75kDa.

Target Information

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.