Thermo Fisher Scientific MTHFR Monoclonal Antibody (5D3)
MTHFR 단백질 검출용 Mouse Monoclonal Antibody (Clone 5D3). Western blot, IHC, ELISA 등 다양한 응용에 적합. Human 및 Rat 시료 반응성. 75kDa MTHFR 단백질 인식. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Rat |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5D3 |
| Immunogen | Purified recombinant fragment of human MTHFR expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154428 |
Product Specific Information
MA5-15844 targets MTHFR in indirect ELISA, IHC, and WB applications and shows reactivity with Human and Rat samples.
The immunogen is a purified recombinant fragment of human MTHFR expressed in E. coli.
MA5-15844 detects MTHFR, which has a predicted molecular weight of approximately 75 kDa.
Target Information
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine.
Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer, and acute leukemia.
Mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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