Thermo Fisher Scientific Cripto Monoclonal Antibody (3A6)
Human TDGF1 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. 비결합형 액상 형태이며 4°C 단기, -20°C 장기 보관이 가능합니다. 인간 시료에서 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A6 |
| Immunogen | Purified recombinant fragment of human TDGF1 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11157667 |
Product Specific Information
MA5-15843 targets TDGF1 in WB applications and shows reactivity with human samples.
The MA5-15843 immunogen is a purified recombinant fragment of human TDGF1 expressed in E. coli.
Target Information
Cripto (TDGF1) is a GPI-anchored cell membrane protein involved in Nodal signaling.
Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells.
TDGF1 is expressed both in embryonic stem cells and during early embryonic development, and is reactivated in a wide range of epithelial cancers in adults.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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