Thermo Fisher Scientific PAX6 Polyclonal Antibody
PAX6 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, ICC/IF, IP에 적합합니다. 인간, 마우스, 랫트 등 다양한 종에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. PBS/BSA 완충액에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution / Amount | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 2 publications |
| Immunocytochemistry (ICC/IF) | 1:50 | View 3 publications |
| Immunoprecipitation (IP) | 5 µg | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Sheep, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues C R(267) E E K L R N Q R R Q A S N T P S H I(285) of mouse PAX6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2159813 |
Product Specific Information
PA1-801 detects PAX6 from human, mouse, rat, non-human primate, and ovine samples. This antibody does not detect bovine PAX6 by Western blot.
It has been successfully used in Western blot, immunofluorescence, and immunoprecipitation applications.
By Western blot, this antibody detects a ~47 kDa protein corresponding to PAX6.
The immunogen is a synthetic peptide corresponding to residues C R(267) E E K L R N Q R R Q A S N T P S H I(285) of mouse PAX6.
This sequence is completely conserved in humans, mice, frogs, and chickens.
This peptide (Product # PEP-207) is available for use in neutralization and control experiments.
Target Information
The PAX6 gene encodes a paired box gene 6, a human homolog of the Drosophila gene prd.
It contains both a paired box domain and a homeobox domain, which bind DNA and regulate gene transcription.
This gene is expressed in the developing nervous system and eyes.
Mutations in PAX6 are associated with ocular disorders such as aniridia and Peter’s anomaly.
Alternative splicing results in multiple transcript variants encoding similar or different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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