Thermo Fisher Scientific Phospho-ATF2 (Thr71) Recombinant Rabbit Monoclonal Antibody (ATF2T71-G3), PE
PE 형광 표지된 인산화 ATF2 (Thr71) 특이 재조합 토끼 단일클론 항체로, Flow Cytometry에 최적화됨. 인간 및 생쥐 반응성. HEK293 세포 발현, Protein A/G 정제. 세포 스트레스 신호 연구용.
- 판매단위
- pk
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Applications
- Flow Cytometry (Flow): 5 µL / 1x10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ATF2T71-G3 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr71 of human phospho ATF2 |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896881 |
Additional Formats
- Unconjugated: MA5-36945
- APC: MA5-36948
- FITC: MA5-36947
- Custom conjugation available upon request
Target Information
ATF-2 (also known as CRE-BP1) is a transcription factor that binds to AP-1 and CRE DNA response elements and belongs to the ATF/CREB family of leucine zipper proteins. It interacts with various viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Cellular stress, including genotoxic agents, inflammatory cytokines, and UV irradiation, activates ATF-2 through phosphorylation at Thr69 and Thr71. Both SAPK and p38 MAPK phosphorylate ATF-2 at these sites in vitro and in transfected cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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