Thermo Fisher Scientific Phospho-Histone H3 (Ser28) Recombinant Rabbit Monoclonal Antibody (HisH3S28-D6), APC
APC 형광으로 표지된 재조합 Rabbit Monoclonal 항체로, Histone H3 Ser28 인산화 형태를 검출합니다. 높은 특이성과 민감도를 가지며 Flow Cytometry에 적합합니다. 동물 유래 성분이 없는 일관된 로트 품질을 제공합니다.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HisH3S28-D6 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser28 of human phospho Histone H3 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896877 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened to select the best candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Histone H3 is a DNA-binding protein found in the chromatin of all eukaryotic cells. Together with four core histones, it forms the nucleosome structure.
Histones regulate transcription, DNA repair, replication, and chromosomal stability. Post-translational modifications such as methylation, acetylation, and phosphorylation affect chromatin structure and transcription factor binding.
The N-terminal tail of histone H3 can undergo multiple modifications influencing cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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