Thermo Fisher Scientific MTDH Monoclonal Antibody (OTI1D3), TrueMAB
MTDH 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1D3). Western blot에 최적화되어 있으며, 인간 시료에 반응합니다. Affinity chromatography로 정제된 액상 항체로, PBS/BSA/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 70–582 of human MTDH produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Metadherin (Metastasis adhesion protein), also known as MTDH or LYRIC, is a novel protein localized with tight junction proteins ZO-1 and occludin in polarized epithelial cells. It is recruited during tight junction maturation rather than serving as a structural component. Metadherin is overexpressed in breast cancer tissues and xenografts, with lower expression in normal breast tissue. It binds to lung vasculature via a C-terminal extracellular domain segment, and blocking this domain or inhibiting MTDH has been reported to reduce breast cancer metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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