Thermo Fisher Scientific PTPRM Polyclonal Antibody
Rabbit polyclonal antibody targeting human PTPRM for IHC applications. Reacts with multiple species. Affinity purified, unconjugated, supplied in PBS with sodium azide. Suitable for research use only; store at 4°C or -20°C for long term.
- 카탈로그번호
- PA534142
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested at 12 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Bovine, Horse, Hamster, Human, Mouse, Non-human primate, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from internal region of human PTPRM |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551495 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Bovine, Bat, Horse, Rabbit (100%)
Opossum, Chicken (94%).
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, representing a receptor-type PTP.
The extracellular region contains a MAM domain, an Ig-like domain, and four fibronectin type III-like repeats.
It mediates cell-cell aggregation through interaction with another molecule of this PTP on adjacent cells and can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for downstream signaling in response to cell-cell adhesion.
Alternative splicing results in multiple transcripts encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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