Thermo Fisher Scientific RHOH Monoclonal Antibody (3D3)
인간 RHOH 단백질을 인식하는 Mouse IgG2a 단클론 항체로, ELISA 등 연구용으로 사용됩니다. GST 태그가 포함된 RHOH 전장 재조합 단백질을 면역원으로 제작되었으며, PBS 기반 액상 형태로 제공됩니다. -20°C에서 보관하며 동결/해동을 피해야 합니다.
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- H00000399-M03
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- pk
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Thermo Fisher Scientific RHOH Monoclonal Antibody (3D3)
Applications
- ELISA (ELISA)
Tested Dilution: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3D3 |
| Immunogen | RHOH (AAH14261.1, 1–191 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MLSSIKCVLV GDSAVGKTSL LVRFTSETFP EAYKPTVYEN TGVDVFMDGI QISLGLWDTA GNDAFRSIRP LSYQQADVVL MCYSVANHNS FLNLKNKWIG EIRSNLPCTP VLVVVTQTDQ REMGPHRASC VNAMEGKKLA QDVRAKGYLE CSALSNRGVQ QVFECAVRTA VNQARRRNRR RLFSINECKI F
Target Information
The Rho subfamily of small GTP-binding proteins mediates many fundamental cellular functions. Members such as Rho, Rac, and CDC42 regulate actin reorganization and affect cellular responses including adhesion, cytokinesis, and motility.
RhoH (also known as TTF, Translocation Three Four) is distinct from most small G proteins. While most are ubiquitously expressed, RhoH is expressed only in hemopoietic cells and tissues. Translocations and frequent RhoH mutations have been detected in primary lymphoma cells, and expression has been observed in activated neutrophils.
RhoH is GTPase-deficient, remaining in a GTP-bound activated state. It may play a role in T cell differentiation and cytoskeleton organization. The RhoH/TTF (ARHH) gene maps to chromosome 4p13 and encodes a 191-amino acid polypeptide.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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