Thermo Fisher Scientific Phospho-Rb (Thr826) Recombinant Rabbit Monoclonal Antibody (17H6L55)
Rb 단백질의 Thr826 인산화 형태를 특이적으로 인식하는 재조합 토끼 단클론 항체. Western blot에 적합하며, 인간에 반응하고 마우스, 랫, 소에도 예측 반응. Protein A 정제, 0.5 mg/mL 농도, PBS 완충액에 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 17H6L55 |
| Immunogen | Peptide corresponding to human Phospho-Rb (Thr826) [aa824–aa830] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2811728 |
Product Specific Information
This antibody is predicted to react with Mouse, Rat, and Bovine.
Target Information
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms complexes with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription, and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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