Thermo Fisher Scientific IDH1 Polyclonal Antibody
IDH1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. HepG2 lysate를 양성 대조로 권장하며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 13 amino acid peptide near the carboxy terminus of human IDH1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152475 |
Product Specific Information
- Suggested positive control: HepG2 cell lysate
- PA5-20976 can be used with blocking peptide PEP-1090.
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one utilizing NAD(+) and the other NADP(+).
Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent (mitochondrial) and two NADP(+)-dependent (one mitochondrial, one cytosolic).
The NADP(+)-dependent cytosolic isozyme encoded by this gene functions in cytoplasmic and peroxisomal NADPH production. It contains a PTS-1 peroxisomal targeting sequence and plays roles in intraperoxisomal reductions and NADPH regeneration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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