Thermo Fisher Scientific IDH2 Polyclonal Antibody
IDH2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. WB 및 IHC 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 에너지 대사 관련 단백질 분석에 활용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid peptide near the amino terminus of human IDH2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage store at -20°C. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11151948 |
Product Specific Information
- Suggested positive control: human heart tissue lysate
- PA5-20977 can be used with blocking peptide PEP-1091
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one utilizing NAD as the electron acceptor and the other NADP.
Five isocitrate dehydrogenases have been reported: three NAD-dependent isocitrate dehydrogenases localized to the mitochondrial matrix, and two NADP-dependent isocitrate dehydrogenases, one mitochondrial and the other predominantly cytosolic.
Each NADP-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP-dependent isocitrate dehydrogenase found in the mitochondria, playing a role in intermediary metabolism and energy production. It may associate or interact with the pyruvate dehydrogenase complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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