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Thermo Fisher Scientific Human WISP-3 Recombinant Protein, PeproTech
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Thermo Fisher Scientific

Thermo Fisher Scientific Human WISP-3 Recombinant Protein, PeproTech

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인체 유래 WISP-3 재조합 단백질로, E. coli에서 발현된 36.8 kDa 단백질입니다. ≥98% 고순도로 정제되었으며, 세포 증식 활성(ED50 0.2–0.3 µg/ml)을 보입니다. 연구용으로 WNT1 신호경로 및 골격 발달 관련 연구에 적합합니다.

카탈로그번호
120-20-xxx (2개 옵션)
브랜드
Thermo Fisher Scientific
카테고리
Protein
판매단위
pk

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2개 옵션
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마지막 업데이트 2025. 08. 05. 오전 09:19
Thermo Fisher Scientific 120-20-01M Human WISP-3 Recombinant Protein, PeproTech 4 x 250 ug pk판매 단위 pk
재고 1개
5,866,000원VAT 포함 6,452,600원
Thermo Fisher Scientific 120-20-500 Human WISP-3 Recombinant Protein, PeproTech 2 x 250 ug pk판매 단위 pk
재고 1개
3,571,800원VAT 포함 3,928,980원
재고문의·견적요청 옵션은 실시간 상담으로 납기를 확인해 드립니다 · 연구비 카드 결제 가능

Thermo Fisher Scientific · Thermo Fisher Scientific Human WISP-3 Recombinant Protein, PeproTech

Applications

Immunoprecipitation (IP)

Functional Assay

In vitro Assay (IV)

Miscellaneous PubMed (Misc)

Product Specifications

항목 내용
Species Human
Published Species Human
Expression System E. coli
Amino Acid Sequence TGPLDTTPEG RPGEVSDAPQ RKQFCHWPCK CPQQKPRCPP GVSLVRDGCG CCKICAKQPG EICNEADLCD PHKGLYCDYS VDRPRYETGV CAYLVAVGCE FNQVHYHNGQ VFQPNPLFSC LCVSGAIGCT PLFIPKLAGS HCSGAKGGKK SDQSNCSLEP LLQQLSTSYK TMPAYRNLPL IWKKKCLVQA TKWTPCSRTC GMGISNRVTN ENSNCEMRKE KRLCYIQPCD SNILKTIKIP KGKTCQPTFQ LSKAEKFVFS GCSSTQSYKP TFCGICLDKR CCIPNKSKMI TIQFDCPNEG SFKWKMLWIT SCVCQRNCRE PGDIFSELKI L
Molecular Weight 36.8 kDa
Class Recombinant
Type Protein
Purity ≥ 98% (SDS-PAGE gel & HPLC)
Endotoxin Concentration < 1 EU/µg
Activity ED50 determined by dose-dependent proliferation of MCF-7 cell line (expected ED50: 0.2–0.3 µg/ml)
Conjugate Unconjugated
Form Lyophilized
Purification Purified
Contains No preservative
Storage Conditions -20°C

Product Specific Information

  • Catalog No. 120-20-1MG: Provided as 4 × 250 µg (120-20-250UG)
  • Catalog No. 120-20-500UG: Provided as 2 × 250 µg (120-20-250UG)
  • Recombinant Human WISP-3 is a 36.8 kDa protein containing 331 amino acids.
  • Composed of four structural domains:
    1. IGF binding protein (IGFBP) domain
    2. von Willebrand Factor C (VWFC) domain
    3. Thrombospondin type-1 repeat (TSP type-1) domain
    4. C-terminal cysteine knot-like (CTCK) domain
  • Shipped at ambient temperature. Refer to lot-specific Certificate of Analysis for storage, handling, and reconstitution details.

Target Information

WISP3 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, belonging to the connective tissue growth factor (CTGF) family.
WNT1 proteins are cysteine-rich, glycosylated signaling molecules involved in diverse developmental processes.
CTGF family members share four conserved cysteine-rich domains:

  • Insulin-like growth factor-binding domain
  • von Willebrand factor type C module
  • Thrombospondin domain
  • C-terminal cystine knot-like domain

WISP3 is overexpressed in colon tumors and may act downstream of WNT1 in malignant transformation.
Mutations in WISP3 are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating its essential role in skeletal growth and cartilage homeostasis.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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