Thermo Fisher Scientific CD19 Monoclonal Antibody (eBio1D3 (1D3)), PE, eBioscience
마우스 CD19를 인식하는 eBio1D3 (1D3) 단클론 항체로, PE 형광표지되어 유세포분석(Flow Cytometry)에 적합합니다. B세포 발현 분석에 활용되며, 0.125 µg/test 권장 농도로 사용 가능합니다. 4°C 보관, 동결 금지.
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카탈로그
4개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD19 Monoclonal Antibody (eBio1D3 (1D3)), PE, eBioscience
Applications
- Flow Cytometry (Flow)
Tested dilution: 0.125 µg/test
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published species | Hamster, Human, Mouse |
| Host / Isotype | Rat / IgG2a, kappa |
| Recommended Isotype Control | Rat IgG2a kappa Isotype Control (eBR2a), PE, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | eBio1D3 (1D3) |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_657661 |
Additional Available Formats
- Unconjugated
- Alexa Fluor 561, 660, 700
- APC, APC-eFluor 780
- Biotin
- Brilliant UV / Violet / Yellow series
- eFluor 450, 506, 660
- FITC
- Functional Grade
- NovaFluor series (Blue, Red, UV, Violet, Yellow)
- PE-Cyanine5, 5.5, 7
- PE-eFluor 610
- PerCP-Cyanine5.5
- Super Bright series (436, 600, 645, 702, 780)
- Request custom conjugation
Product Specific Information
Description:
The eBio1D3 monoclonal antibody reacts with mouse CD19, a 95 kDa transmembrane glycoprotein expressed on B cells during all developmental stages except terminally differentiated plasma cells. Follicular dendritic cells also express CD19. CD19 forms a multimolecular complex with CD21, CD81, and MHC class II that associates with the BCR, mediating tyrosine phosphorylation, calcium flux, and B cell proliferation.
Applications Reported:
Reported for use in flow cytometric analysis.
Applications Tested:
Tested by flow cytometric analysis of mouse splenocytes. Recommended ≤0.125 µg per test (100 µL final volume). Optimal antibody concentration should be titrated for specific assay conditions.
Excitation/Emission:
488–561 nm / 578 nm
Laser Compatibility: Blue, Green, Yellow-Green lasers
Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains, expressed on nearly all peripheral B cells and certain myeloid leukemia cells. It serves as a key regulator of B cell receptor signaling, lowering the activation threshold and amplifying antigen receptor-mediated responses. Mutations in CD19 can lead to hypogammaglobulinemia, while overexpression is linked to B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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