Thermo Fisher Scientific ALS2CR2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:250-1:500

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide: S(399) P W S E L E F Q F P D D K D P V W E F(418) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ALS2CR2,uniProtId:Q8K4T3-1,ncbiNodeId:10090,antigenRange:399-418,antigenLength:418,antigenImageFileName:PA1-4314_ALS2CR2_Q8K4T3-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4314_ALS2CR2_Q8K4T3-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2197581

Product Specific Information

PA1-4314 detects the PAPK protein in mouse samples.

PA1-4314 has been successfully used in Western blot procedures.

The PA1-4314 immunizing peptide corresponds to amino acid residues 399-418 of the mouse PAPK protein.

Target Information

This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.