Thermo Fisher Scientific ALS2CR2 Polyclonal Antibody
Thermo Fisher Scientific의 ALS2CR2 폴리클로날 항체는 마우스 시료에서 PAPK 단백질 검출에 적합합니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 2–8°C에서 보관 가능합니다.
- 카탈로그번호
- PA14314
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:250–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide: S(399) P W S E L E F Q F P D D K D P V W E F(418) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2197581 |
Product Specific Information
- PA1-4314 detects the PAPK protein in mouse samples.
- Successfully used in Western blot procedures.
- The immunizing peptide corresponds to amino acid residues 399–418 of the mouse PAPK protein.
Target Information
This gene encodes a protein belonging to the serine/threonine protein kinase STE20 subfamily.
One of the active site residues in the protein kinase domain is altered, making it a pseudokinase.
It is part of a complex involved in the activation of serine/threonine kinase 11 (STK11), a master kinase regulating cell polarity and energy metabolism.
This complex is essential for G1 cell cycle arrest mediated by STK11.
The encoded protein can interact with the X chromosome-linked inhibitor of apoptosis protein, enhancing anti-apoptotic activity via the JNK1 pathway.
Two pseudogenes for this gene are located on chromosomes 1 and 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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