Thermo Fisher Scientific ESCO1 Polyclonal Antibody
Human ESCO1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200~1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 버퍼에 보관. 세포 내 염색 및 단백질 발현 연구용으로 적합.
- 카탈로그번호
- PA560000
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ESCO1 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ESCO1. Recombinant protein control fragment (Product #RP-98281). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641123 |
Product Specific Information
Immunogen sequence:
ERAPENCHLA NEIKPSDPPL DNQMKHSFDS ASNKNFSQCL ESKLENSPVE NVTAASTLLS QAKIDTGENK FPGSAPQQHS ILSNQTSKSS DNRETPRNHS LPKCNSHLEI
Highest antigen sequence identity to the following orthologs:
- Mouse: 59%
- Rat: 64%
Target Information
EFO1 (Establishment factor-like protein 1), also known as ESCO1 (establishment of cohesion 1 homolog1) or ESO1, is a member of the acetyltransferase family (GCN5 subfamily). It is a ubiquitously expressed nuclear protein that plays an important role in sister chromatid cohesion.
At its C-terminus, EFO1 contains an H2C2 zinc finger motif and an acetyltransferase domain that exhibits acetyltransferase activity in vivo. Its N-terminus, containing two domains similar to alpha- and beta-type linker histone proteins, is essential for EFO1 association with chromosomes.
EFO1 couples cohesion and DNA replication processes, ensuring proper pairing of sister chromatids. It is phosphorylated during mitosis, which may regulate its activity. Three EFO1 isoforms exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.