Thermo Fisher Scientific NEK2 Recombinant Rabbit Monoclonal Antibody (JE37-74)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,00-1:2,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

JE37-74

Immunogen

Synthetic peptide within Human NEK2 aa 1-50/445. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NEK2,uniProtId:P51955-1,ncbiNodeId:9606,antigenRange:1-50,antigenLength:445,antigenImageFileName:MA5-50807_NEK2_P51955-1_Rabbit.svg,antigenImageFileNamePDP:MA5-50807_NEK2_P51955-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 0.05% BSA, 40% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3093104

Product Specific Information

Positive control: A549 cell lysate, Hela cell lysate.

Predicted band size: 52 kDa

Subcellular Location: Nucleus, nucleolus, Cytoplasm.

Target Information

NEK2 is involved in cell cycle regulation and is essential for faithful chromosome segregation. NEK2 is a gene that encodes for a serine/threonine-protein kinase. This protein plays a crucial role in the regulation of mitosis and is primarily located in the centrosome. During the G1 phase, the protein is undetectable, but its levels progressively increase throughout the S phase, reaching their peak in late G2 phase. The gene has several alternatively spliced transcript variants that encode different isoforms with distinct C-termini. NEK2 is associated with several diseases, including Retinitis Pigmentosa 67 and Retinitis Pigmentosa.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.