Thermo Fisher Scientific PSMD11 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:400

-

Immunocytochemistry (ICC/IF)

1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide within human PSMD11 aa 200-500/422. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PSMD11,uniProtId:O00231-1,ncbiNodeId:9606,antigenRange:200-500,antigenLength:422,antigenImageFileName:PA5-144656_PSMD11_O00231-1_Rabbit.svg,antigenImageFileNamePDP:PA5-144656_PSMD11_O00231-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 0.1% BSA, 40% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3094044

Product Specific Information

Positive control: 293T cell lysate, HepG2 cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, PC-3 cell lysate, Hela cell lysate, mouse testis tissue lysate, rat testis tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, mouse testis tissue, NIH/3T3.

Predicted band size: 47 kDa

Subcellular Location: Cytoplasm, Nucleus.

Target Information

The 26S proteasome (PSMD11) is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The protein is a non-ATPase subunit of the 19S regulator.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.