Thermo Fisher Scientific Urokinase Polyclonal Antibody
Urokinase 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human 및 Rat 시료에 반응합니다. WB와 ICC/IF에 적합하며, 고순도 Affinity chromatography로 정제되었습니다. 4°C 단기 보관, -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within Human Urokinase aa 10–200/431 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3093529 |
Product Specific Information
- Positive control: PC-3M cell lysate, MCF-7 cell lysate, LANCAP cell lysate, rat kidney tissue lysate, rat stomach tissue lysate, PC-3M
- Predicted band size: 49 kDa
- Subcellular Location: Secreted
Target Information
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation.
A specific polymorphism in this gene may be associated with late-onset Alzheimer’s disease and decreased affinity for fibrin-binding.
This protein converts plasminogen to plasmin by cleavage of an Arg-Val bond in plasminogen.
Plasmin then cleaves this protein at a Lys-Ile bond to form a two-chain derivative (HMW-uPA), which can be further processed into LMW-uPA.
LMW-uPA is proteolytically active but does not bind to the uPA receptor.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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