Thermo Fisher Scientific CETN3 Monoclonal Antibody (OTI1E3), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The CETN3 protein contains four EF-hand calcium-binding domains and belongs to the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae, which plays a key role in centrosome duplication and separation.
In human and mammalian cells, multiple centrin forms have been identified, some associated with centrosome fractions. CETN3 is among the most abundant centrins at the centrosome, suggesting a similar function to its yeast counterpart.
Alternatively spliced transcript variants encoding different isoforms have also been reported.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.