Thermo Fisher Scientific MARK3 Monoclonal Antibody (OTI3D8), TrueMAB
Human MARK3 단백질(aa 473-729)을 항원으로 한 Mouse IgG2b 단클론 항체로, Western blot에 1:2,000 희석 비율로 검증됨. Lyophilized 형태이며 PBS buffer(8% trehalose)로 보관. 세포 극성 및 미세소관 관련 단백질 인산화 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 473–729 of human MARK3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MARK3 is a kinase involved in regulating cell polarity through phosphorylation of microtubule-associated proteins (MAPs). Activated MARK3 phosphorylates tau proteins, MAP2, and MAP4. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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