Thermo Fisher Scientific H1N1 NP Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-1 µg/mL

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH-coupled synthetic peptide from C-terminal of Influenza A (H1N1) 2009 virus NP protein (GenBank: CY040002).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

Product Specific Information

Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.

nfluenza A (H1N1) virus is a subtype of influenzavirus A and the most common cause of influenza (flu) in humans. A strain of swine-origin H1N1 was responsible for the 2009 flu pandemic. NP (nucleocapsid protein) encapsulates the negative strand viral RNA, protecting it from nucleases. NP is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway.GenScript Rabbit Anti-H1N1 NP Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of Influenza A (H1N1) 2009 virus NP protein (GenBank: CY040002).

Target Information

Influenza viruses consists of three types (Influenza A, B, and C), which make up three of the five genera in the Orthomyxoviridae family. Commonly know as the flu, influenza strains can affect both birds and mammals. Influenza strains form roughly spherical particles and are similar in composition with viral envelope containing two main types of glycoproteins (hemagglutinin and neuraminidase), wrapped around the central core of the viral RNA genome and other viral proteins that package and protect the RNA. Unusually for a virus, the influenzavirus genome is not a single piece of nucleic acid; rather a seven to eight segmented fragments of negative-sense RNA with each fragment expressing different viral proteins. Influenza spreads seasonally, resulting in about three to five million yearly cases of severe illness and about 250,000 to 500,000 deaths annually or into the millions in pandemic years.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.