Thermo Fisher Scientific ATP1A1 Polyclonal Antibody

Applications and Tested Dilution

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Product Specifications

Product Specific Information

Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.

ATP1A1, also known as Na⁺/K⁺ ATPase alpha-1 subunit, belongs to the family of P-type cation transport ATPases and the Na⁺/K⁺ ATPase subfamily.
Na⁺/K⁺ ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na⁺ and K⁺ ions across the plasma membrane.
These gradients are essential for:

• Osmoregulation
• Sodium-coupled transport of various organic and inorganic molecules
• Electrical excitability of nerve and muscle cells

This enzyme consists of two subunits:

1. A large catalytic subunit (alpha)
2. A smaller glycoprotein subunit (beta)

GenScript Rabbit Anti-ATP1A1 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 800–850 of human ATP1A1 (Swiss Prot: P05023).

Target Information

The protein encoded by this gene belongs to the family of P-type cation transport ATPases and the subfamily of Na⁺/K⁺ ATPases.
Na⁺/K⁺ ATPase is an integral membrane protein responsible for maintaining electrochemical gradients of Na⁺ and K⁺ ions across the plasma membrane.
These gradients are crucial for:

• Osmoregulation
• Sodium-coupled transport
• Electrical excitability of nerve and muscle

The enzyme is composed of:

• A large catalytic subunit (alpha)
• A smaller glycoprotein subunit (beta)

The catalytic subunit of Na⁺/K⁺ ATPase is encoded by multiple genes.
This gene encodes the alpha 1 subunit, and multiple transcript variants encoding different isoforms have been identified.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.