Thermo Fisher Scientific hCG beta Monoclonal Antibody (HCG-61)
인간 hCG 베타 단백질을 인식하는 단클론 항체로, ICC/IF 및 ELISA에 사용 가능. Mouse IgG2b 형식이며 Protein A로 정제됨. 1 mg/mL 농도의 액상 형태로 제공되며 4°C에서 보관. 연구용으로만 사용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HCG-61 |
| Immunogen | Human chorionic gonadotropin (hCG beta, UniProt ID: P0DN86-1, Range: 1–165) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1073666 |
Product Specific Information
This antibody reacts with association constant 5.1 × 10¹⁰ l/mol.
Cross-reactivity (%) determined by double-antibody RIA using unlabeled hormones:
- beta-hCG: 77%
- alpha-hCG: 1.3%
- hLH: 0.86%
- hFSH: < 0.5%
- hTSH: < 0.5%
Target Information
hCG beta is the beta chain of Human chorionic gonadotropin (hCG), a 40 kDa glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10–12 days after conception.
hCG consists of alpha and beta subunits that are non-covalently associated. The alpha subunit is similar to those of pituitary hormones (FSH, LH, TSH), while the beta subunit confers biological specificity.
During early pregnancy, hCG stimulates the corpus luteum to produce progesterone, maintaining the secretory endometrium.
In non-pregnant individuals, hCG is present only in trace amounts but rises sharply during pregnancy.
Diseases associated with hCG dysfunction include gestational trophoblastic tumor and hydatidiform mole.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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