
Thermo Fisher Scientific PROZ Monoclonal Antibody (OTI3E5), TrueMAB
인간 PROZ 단백질을 인식하는 Mouse IgG2a 단클론 항체로 Western blot에 적합. 고순도 Affinity chromatography 정제, 1 mg/mL 농도. PBS/BSA/glycerol buffer에 보관하며 -20°C에서 안정적. 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E5 |
| Immunogen | Human recombinant protein fragment (aa 115–400 of human PROZ) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PROZ (Protein Z) is a vitamin K-dependent plasma glycoprotein (62 kDa, 396 amino acids) involved in the coagulation cascade. It contains a gla-rich region, two EGF-like domains, and a trypsin-like domain but lacks catalytic serine residue. Protein Z functions as a cofactor for protein Z-related protease inhibitor (ZPI) in the degradation of factor Xa, enhancing the reaction up to 1000-fold. It is structurally related to factors VII, IX, X, and protein C. Deficiency may be associated with either thrombosis or bleeding tendencies.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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