Thermo Fisher Scientific STAB2 Monoclonal Antibody (OTI2A6), TrueMAB
인간 STAB2 단백질을 인식하는 단클론 항체로 IHC(P)에서 1:150 희석으로 사용 가능. TrueMAB 형식으로 높은 특이성과 재현성을 제공. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol 버퍼에 보관. -20°C에서 안정적으로 보관 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1914–2194 of human STAB2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a large transmembrane receptor protein that may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging.
The protein contains:
- 7 fasciclin domains
- 15 epidermal growth factor (EGF)-like domains
- 2 laminin-type EGF-like domains
- A C-type lectin-like hyaluronan-binding Link module
It is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node.
The receptor binds and endocytoses ligands such as hyaluronan, low-density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products.
Supporting its possible role as a scavenger receptor, the protein cycles between the plasma membrane and lysosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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