Thermo Fisher Scientific WDR5 Polyclonal Antibody
WDR5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin) 분석에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며, Affinity chromatography로 정제된 고순도 항체입니다. 연구용으로만 사용 가능합니다.
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- PA5102553
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human WDR5 (Accession P61964), corresponding to amino acid residues M1–S49 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851955 |
Product Specific Information
Antibody detects endogenous levels of total WDR5.
Target Information
Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).
Acts as a molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation by promoting disassembly of transcriptional regulatory complexes.
Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruitment of EGLN1/PHD2 to the HSP90 pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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