Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT14/7054R)
사람 세포 반응성을 가진 재조합 토끼 단클론 항체로, Cytokeratin 14을 표적하여 편평상피세포 마커로 사용. Western Blot 및 면역조직화학 분석에 적합하며, 고순도 Protein A/G 정제. 연구용으로 안정적인 액상 형태 제공.
- 카탈로그번호
- 3861RBM26P1ABX
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | KRT14/7054R |
| Immunogen | Recombinant human KRT14 fragment (around aa350–472) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, found in both keratinizing tissues (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). At least 20 different CKs have been identified. They are classified into two types: type I (acidic polypeptides) and type II (basic polypeptides).
Keratin 14, a type I low molecular weight keratin, forms pairs with keratin 5 and distinguishes stratified epithelial cells from simple epithelial cells. It is useful for identifying squamous cell carcinomas and serves as a prognostic marker in breast carcinomas.
Both acidic and basic keratins are expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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