Thermo Fisher Scientific MEK1 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal MEK1 항체. Western blot에 1:500–1:1,000 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되어 순도 >95%. PBS/glycerol buffer에 보관되며, 장기 보관 시 -20°C 권장.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 180–230 of Human MEK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803372 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
MAP2K1 (MEK1) kinase is a dual-specificity protein kinase involved in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation.
It is activated by various growth factors, cytokines, and membrane-dependent depolarization and calcium influx.
Activation occurs via phosphorylation of serine residues 218 and 222 by Raf1.
MEK1 plays roles in stress-activated responses, apoptosis, and cytokine-induced proliferation.
Mutations in MAP2K1 can lead to cardiofaciocutaneous syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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