Thermo Fisher Scientific CACNA1F Polyclonal Antibody
Rabbit polyclonal antibody against human CACNA1F for WB and IHC applications. Recognizes voltage-sensitive calcium channel alpha-1F isoform. Lyophilized form, reconstitute in sterile water. Suitable for research use only.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from human CACNA1F conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: CACNA1F.
Target Information
Voltage-sensitive calcium channels (VSCC) mediate calcium ion entry into excitable cells and are involved in various calcium-dependent processes such as muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death.
The alpha-1F isoform gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the high-voltage activated (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and omega-agatoxin-IIIA (omega-Aga-IIIA), but are insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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