Thermo Fisher Scientific CACNA1I Polyclonal Antibody
CACNA1I 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody로 인간, 생쥐, 랫트 반응성을 보입니다. Western blot 및 IHC에 적합하며, 동결 건조 형태로 제공됩니다. 신경세포 칼슘 신호 연구에 활용 가능합니다.
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Thermo Fisher Scientific CACNA1I Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Immunohistochemistry – Free Floating (IHC (Free)) | 1:300 |
| Miscellaneous PubMed (Misc) | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from a cytoplasmic domain of human CACNA1I (Cav3.3) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity: CACNA1I.
Target Information
CaV3.3 encodes the pore-forming alpha subunit of a voltage-gated calcium channel.
This protein is a member of the low voltage-activated, T-type calcium channel family.
CaV3.3 channels exhibit slower activation and inactivation compared to other T-type channels and may be involved in neuronal calcium signaling.
Alternate splicing results in multiple transcript variants.
Voltage-gated calcium channels (CaV) mediate calcium influx in response to depolarization and regulate intracellular processes such as contraction, secretion, neurotransmission, and gene expression.
Diseases associated with CACNA1I include Childhood Absence Epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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