Thermo Fisher Scientific CACNB1 Polyclonal Antibody
Rabbit polyclonal antibody targeting CACNB1 for WB and IHC applications. Reacts with human, mouse, and rat. Lyophilized form with no preservative; store at 4°C short term or -20°C long term. Designed for research use only.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of mouse CACNB1 (CAB1) conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide shares 98% identity with rat and human sequences.
- Specificity: CACNB1.
Target Information
Calcium Channel 1 is a protein encoded by the CACNB1 gene and belongs to the calcium channel beta subunit family.
It plays a key role in calcium channel function by:
- Modulating G protein inhibition
- Increasing peak calcium current
- Controlling alpha-1 subunit membrane targeting
- Shifting voltage dependence of activation and inactivation
Dysfunction of Calcium Channel 1 protein is associated with malignant hyperthermia susceptibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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