Thermo Fisher Scientific Neuropilin 1 Polyclonal Antibody
Mouse Neuropilin-1 단백질을 특이적으로 인식하는 Rabbit Polyclonal Antibody. IHC(P)에서 1:200~1:1,000 희석으로 사용 가능. Protein A 및 항원 친화 크로마토그래피로 정제. VEGF 유도 혈관형성 연구 및 신경계 발현 분석에 적합.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the center region of the Mouse Neuropilin-1 (NRP1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2788514 |
Product Specific Information
This antibody has specificity for Mouse Neuropilin-1.
Target Information
Neuropilin 1 is a 923 amino acid membrane-bound coreceptor belonging to the neuropilin family, containing two CUB domains, two F5/8 type C domains, and a MAM domain. It forms heterodimers with Neuropilin 2 (NRP2) and binds to plexin (PLXNB1) to form semaphorin receptors.
Primarily expressed in the nervous system, Neuropilin 1 is involved in cardiovascular development, angiogenesis, axon guidance, neuronal circuit formation, cell survival, neuronal migration, and organogenesis. It functions as a receptor for both semaphorins and vascular endothelial growth factor (VEGF), regulating VEGF-induced angiogenesis. Neuropilin 1 may also be associated with advanced prostate carcinoma and breast cancer progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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