Thermo Fisher Scientific VDAC Polyclonal Antibody
VDAC1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC/IF, IP 등 다양한 응용에 적합. 방부제 무첨가 제품으로 인체 Porin/VDAC1에 특이적. 연구용으로 세포 대사 및 아폽토시스 연구에 활용 가능.
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Thermo Fisher Scientific VDAC Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the center region of Human VDAC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Refrigerate at 2–8°C for up to 1 month. For long-term storage, store at –20°C. |
| Shipping Conditions | Wet ice |
| RRID | AB_2788517 |
Product Specific Information
- Preservative-free formulation.
- Recommended to add sodium azide to prevent contamination (final concentration 0.05%–0.1%).
- This antibody has specificity for Human Porin/VDAC1.
Target Information
Voltage-dependent anion channel (VDAC) proteins are abundant pore-forming proteins located in the mitochondrial outer membrane and also expressed in the plasma membrane.
At least three different VDAC genes have been identified in vertebrates.
VDAC proteins play essential roles in cellular metabolism and apoptosis initiation.
VDAC forms a major pathway for metabolite exchange between cytosol and mitochondria (e.g., ADP/ATP, succinate, citrate).
VDAC1 in the plasma membrane may regulate apoptosis via redox activity.
Usage Note
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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