Thermo Fisher Scientific Human BMPR1A (ALK3), GST Tag Recombinant Protein

Thermo Fisher Scientific Human BMPR1A (ALK3), GST Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution

• Assay-dependent

Product Specifications

Product Specific Information

For maximum recovery, please spin prior to use.
Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use materials in original packaging until exhausted.
For larger sizes, reduce freeze/thaw cycles by preparing aliquots (not below 20 µL).
Do not store kinase diluted.
Properly stored at -80°C, this product is guaranteed for 6 months from date of purchase.

Protein Form: Catalytic

Target Information

BMPR1A is a Type I member of the TGF-beta receptor superfamily of transmembrane serine/threonine kinases that phosphorylate intracellular SMADs in response to bone morphogenic proteins.
These receptors are closely related to activin receptors ACVR1 and ACVR2.
Ligands of these receptors belong to the TGF-beta superfamily.
TGF-betas and activins signal through heteromeric complexes composed of type I (50–55 kDa) and type II (70–80 kDa) receptors.
Type II receptors bind ligands independently but require type I receptors for signaling, whereas type I receptors require type II receptors for ligand binding.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.