Thermo Fisher Scientific Human LRRK2 [D1994A], GST Tag Recombinant Protein

Applications

Tested Dilution

Publications

Kinase Assay (KA)

Assay-dependent

-

Product Specifications

Species

Human

Expression System

Baculovirus

Amino acid sequence

970-2527; D1994A

Tag

GST-tag

Molecular weight

205 kDa

Class

Recombinant

Type

Protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

purified

Storage buffer

proprietary buffer

Contains

no preservative

Storage conditions

-80° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Dry ice

Product Specific Information

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.

Related Links:
• LRRK2 tools for advancing Parkinson`s disease research
• Kinase protein portfolio
• LanthaScreen™ Eu Kinase Binding Assay
• LanthaScreen™ Activity Assay

Protein Form: Catalytic

Target Information

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in LRRK2 (R1441C Mutant) have been associated with Parkinson disease-8.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.