Thermo Fisher Scientific PRMT6 Monoclonal Antibody (4G2)
PRMT6 단백질을 인식하는 Thermo Fisher Scientific의 단일클론 항체로, Western blot과 ELISA에 적합합니다. 인간 및 비인간 영장류 시료에서 반응하며, 비결합형(mouse IgG1) 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G2 |
| Immunogen | Purified recombinant fragment of human PRMT6 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10984367 |
Product Specific Information
MA5-15584 targets PRMT6 in indirect ELISA and Western blot applications and shows reactivity with human and non-human primate samples.
The immunogen is a purified recombinant fragment of human PRMT6 expressed in E. coli.
MA5-15584 detects PRMT6, which has a predicted molecular weight of approximately 42 kDa.
Target Information
Protein arginine N-methyltransferase 6 (PRMT6) demonstrates type I PRMT activity, capable of forming both omega-N monomethylarginine and asymmetric dimethylarginine derivatives on recombinant glycine- and arginine-rich substrates.
Acts as a transcriptional coactivator of several steroid hormone receptors, including ESR1, ESR2, PGR, and NR3C1.
Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator.
May play a role in innate immunity against HIV-1 by methylating and impairing the function of viral proteins such as Tat, Rev, and nucleocapsid protein p7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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