Thermo Fisher Scientific SMC1 Monoclonal Antibody (5B6)
SMC1 단백질을 검출하기 위한 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 5B6). Western blot, IHC, ICC, Flow cytometry, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Protein G 정제, 1 mg/mL 농도. 연구용 전용 제품.
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Thermo Fisher Scientific SMC1 Monoclonal Antibody (5B6)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5B6 |
| Immunogen | Purified recombinant fragment of human SMC1 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10980475 |
Product Specific Information
MA5-15583 targets SMC1 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human samples.
The immunogen is a purified recombinant fragment of human SMC1 expressed in E. coli.
MA5-15583 detects SMC1 with a predicted molecular weight of approximately 143 kDa.
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in nuclear events that involve chromosome structural changes, including mitotic chromosome organization, DNA recombination and repair, and transcriptional repression.
SMC1 and SMC3 form a heterodimeric complex essential for metaphase progression and sister chromatid cohesion. Mutations in SMC1 can lead to Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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