
Thermo Fisher Scientific TBX3 Recombinant Superclonal Antibody (22HCLC)
TBX3 단백질을 인식하는 Recombinant Superclonal™ 항체로, 높은 특이성과 재현성을 제공합니다. Western blot, ICC/IF, ChIP 등 다양한 응용에 적합합니다. 인간 반응성이 확인되었으며, 원숭이·돼지·쥐에서도 예측 반응성을 보입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | - |
| ChIP assay (ChIP) | 2.5 µg × 10^6 cells | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 22HCLC |
| Immunogen | Protein corresponding to Human TBX3 (aa 305–500) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633115 |
Product Specific Information
This antibody is predicted to react with Monkey, Pig, and Rat.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple recombinant monoclonal antibodies to deliver the sensitivity of polyclonal antibodies and the specificity of monoclonal antibodies, with the lot-to-lot consistency of recombinant production.
While functionally similar to polyclonal antibodies—recognizing multiple epitope sites and providing high sensitivity for low-abundance targets—Superclonal™ antibodies have a defined mixture of light and heavy chains, ensuring reproducibility across lots.
Note: Formerly called “Recombinant Polyclonal Antibody,” now rebranded as “Recombinant Superclonal™ Antibody.” The product and performance remain unchanged.
Target Information
T-box 3 (TBX3) is a member of a conserved gene family characterized by the T-box DNA-binding domain. TBX3 encodes a transcriptional repressor involved in developmental regulation, including anterior/posterior limb axis formation and mammary gland development.
Mutations in TBX3 cause ulnar-mammary syndrome (MIM 181450), affecting limb, gland, tooth, hair, and genital development. TBX3 is also implicated in tumor development and osteoblast differentiation. Overexpression in certain human breast cancer cell lines and immortalization of fibroblasts in vitro have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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