Thermo Fisher Scientific GDNF Recombinant Superclonal Antibody (13HCLC)
GDNF 단백질(aa 78-211)에 특이적인 Rabbit Recombinant Superclonal 항체. WB, IHC, ICC/IF에 사용 가능하며 높은 재현성과 감도를 제공. 단일 클론의 특이성과 다클론 수준의 민감도를 결합한 구조. Human에 반응하며 Monkey, Horse, Pig에서도 예측 반응.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 13HCLC |
| Immunogen | Protein corresponding to Human GDNF (aa 78–211) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633113 |
Product Specific Information
This antibody is predicted to react with Monkey, Horse, and Pig.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of a mixture of multiple recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
Unlike traditional polyclonal antibodies, these recombinant Superclonal™ antibodies maintain batch-to-batch consistency by using a defined mixture of light and heavy chains. This ensures reproducible results and eliminates biological variability.
Note: Formerly called “Recombinant Polyclonal Antibody”, now rebranded as “Recombinant Superclonal™ Antibody”. The product and performance remain unchanged.
Target Information
GDNF (Glial cell line-derived neurotrophic factor) is a glycosylated, disulfide-bonded homodimer first identified as a potent survival factor for midbrain dopaminergic neurons. It has been shown to rescue these neurons in animal models of Parkinson’s disease and is approximately 100 times more effective as a survival factor for spinal motor neurons compared to neurotrophins. GDNF promotes survival and morphological differentiation of dopaminergic neurons and enhances their high-affinity dopamine uptake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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