Thermo Fisher Scientific Phospho-S6 (Ser244) Polyclonal Antibody
Mouse rpS6 단백질의 Ser244 인산화 형태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제됨. -20°C에서 보관, 연구용으로만 사용.
- 카탈로그번호
- PA5143636
- 판매단위
- pk
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Thermo Fisher Scientific Phospho-S6 (Ser244) Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:50
Publications: - [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser244 of mouse rpS6, conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 10mM HEPES (pH 7.5), 100µg/mL BSA, 50% glycerol, 150mM NaCl |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2942864 |
Product Specific Information
Specific for endogenous levels of the ~28 kDa rpS6 protein phosphorylated at Ser244.
Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.
Target Information
Ribosomes catalyze protein synthesis and consist of a small 40S subunit and a large 60S subunit. These subunits include 4 RNA species and approximately 80 distinct proteins. The gene encodes a cytoplasmic ribosomal protein component of the 40S subunit, belonging to the S6E family.
It is the major substrate of ribosomal protein kinases, with five C-terminal serine residues phosphorylated by different kinases. Phosphorylation is induced by various stimuli such as growth factors and mitogens, while dephosphorylation occurs at growth arrest.
This protein may regulate cell growth and proliferation via selective translation of specific mRNA classes. Multiple processed pseudogenes of this gene are dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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