Thermo Fisher Scientific HARS2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human HARS2 protein. Validated for WB and IHC applications. High purity (>95%) affinity-purified preparation. Suitable for protein biosynthesis and Perrault syndrome research. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of human HARS2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719994 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Aminoacyl-tRNA synthetases are enzymes that charge tRNAs with their cognate amino acids. The protein encoded by the HARS2 gene belongs to the class II family of aminoacyl-tRNA synthetases and functions in the synthesis of histidyl-transfer RNA, playing an accessory role in the regulation of protein biosynthesis.
The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes share a bidirectional promoter. Mutations in HARS2 are associated with Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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