Thermo Fisher Scientific CTHRC1 Polyclonal Antibody
CTHRC1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화된 고희석 적용 가능. 인간, 랫트 등에서 높은 반응성 예측. 액상 형태로 4°C 보관, 연구용 전용.
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Thermo Fisher Scientific CTHRC1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:10,000–1:25,000
Predicted Reactivity: Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 193 and 243 of human Collagen triple helix repeat-containing protein 1 (CTHRC1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Target Information
The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein transiently expressed in the arterial wall in response to injury. It contributes to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration.
CTHRC1 is highly expressed in multiple human cancers, including pancreatic cancer, where it plays a significant role in tumor progression and metastasis by regulating migration and adhesion of tumor cells.
Overexpression of CTHRC1 can serve as an independent prognostic marker in gastric cancer. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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