Thermo Fisher Scientific C17orf85 Polyclonal Antibody
C17orf85 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제됨. 인간 시료 반응성, 비결합(Unconjugated) 형태의 액상 제품. 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:10,000–1:25,000
Immunoprecipitation (IP)
- Tested Dilution: 50–100 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 25 and 75 of human Uncharacterized protein C17orf85 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export.
NCBP3 serves as an adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80.
Unlike the conventional CBC with NCBP2, which binds both small nuclear RNA (snRNA) and messenger RNA (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA, thereby playing a role only in mRNA export.
The alternative CBC is particularly important in cellular stress situations such as virus infections, and NCBP3 activity is critical to inhibit virus growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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