Thermo Fisher Scientific SALL4 Monoclonal Antibody (A7A7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:600

-

Immunocytochemistry (ICC/IF)

1:100

-

Flow Cytometry (Flow)

1:500-1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

A7A7

Immunogen

Recombinant protein within human Sall4 aa 903-1053/1053. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SALL4,uniProtId:Q9UJQ4-1,ncbiNodeId:9606,antigenRange:903-1053,antigenLength:1053,antigenImageFileName:MA5-50592_SALL4_Q9UJQ4-1_House_mouse.svg,antigenImageFileNamePDP:MA5-50592_SALL4_Q9UJQ4-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 0.1% BSA, 40% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3091101

Product Specific Information

Positive control: NCCIT cell lysates, NCCIT, human seminoma tissue.

Predicted band size: 112 kDa

Subcellular Location: Cytoplasm, Nucleus.

Target Information

Sall4 protein is encoded by the Sall4 gene located on chromosome 20 in humans and belongs to the Spalt-like protein family. It plays an important role in somatic stem cell maintenance and is studied as a stem cell biomarker. It is a zinc finger transcription factor that is upregulated during development and shown to interact with Oct4 and Sox2. It also forms a complex with Nanog to maintain the pluripotency of Embryonic Stem cells (ESCs). Several current research studies focus on its function as an oncogene and tumor biomarker. Some of the reported target genes of Sall4 include p53, Bmi-1, Bcl2 and XIAP.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.