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Thermo Fisher Scientific PKN2 Recombinant Rabbit Monoclonal Antibody (ARC2274)
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PKN2 단백질을 인식하는 재조합 토끼 단일클론 항체로 Western blot, ICC/IF, ELISA에 적합. HEK293 세포에서 발현되며 높은 특이성과 재현성을 제공. 인간, 마우스, 랫트 반응성. 연구용으로만 사용.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오전 09:33
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Thermo Fisher Scientific MA537978 PKN2 Recombinant Rabbit Monoclonal Antibody (ARC2274) 100 ul pk판매 단위 pk ·
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699,900원VAT 포함 769,890원
Thermo Fisher Scientific · Thermo Fisher Scientific PKN2 Recombinant Rabbit Monoclonal Antibody (ARC2274)
Thermo Fisher Scientific PKN2 Recombinant Rabbit Monoclonal Antibody (ARC2274)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2274 |
| Immunogen | Synthetic peptide (amino acids 1–100 of human PRK2/PKN2, UniProt Q16513) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897896 |
Product Specific Information
- Positive Samples: HeLa, NIH/3T3, Jurkat, C6
- Immunogen sequence:
MASNPERGEI LLTELQGDSR SLPFSENVSA VQKLDFSDTM VQQKLDDIKD RIKREIRKEL KIKEGAENLR KVTTDKKSLA YVDNILKKSN KKLEELHHKL
Target Information
PKN2 (PRK2), a close relative of PKCs, regulates mitosis and cytokinesis.
It plays roles in:
- Cell cycle progression and actin cytoskeleton assembly
- Cell migration, adhesion, and tumor cell invasion
- Transcription activation signaling
- Phosphorylation of CTTN and HDAC5
- RhoA-dependent junction maturation and cytokinesis
- FYN kinase activation for keratinocyte differentiation
- Regulation of epithelial cell movement and invasion
- Inhibition of Akt pro-survival kinase activity
- Rho protein-induced transcriptional activation via c-fos SRF
- Stimulation of HCV RNA replication through NS5B phosphorylation
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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