Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1 Monoclonal Antibody (GT263)
SARS-CoV-2 Spike Protein S1을 특이적으로 인식하는 Mouse Monoclonal Antibody로, SARS-CoV 및 MERS-CoV와 교차 반응하지 않음. WB, IHC, ICC, ELISA 등 다양한 응용에 적합. Protein G로 정제된 액상 시약으로 4°C 또는 -20°C 보관 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| ELISA | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT263 |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of SARS-CoV-2 (COVID-19) Spike. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890584 |
Product Specific Information
- Positive control: SARS-CoV-2 spike (Full length)-transfected 293T cells
- Specificity: Detects SARS-CoV-2 Spike protein; does not cross-react with SARS-CoV or MERS-CoV spike proteins based on testing
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The SARS-CoV-2 Spike Protein consists of S1 and S2 domains and serves as the main surface antigen.
The glycosylated Spike protein and nucleocapsid protein can be detected in infected cell culture supernatants using antisera from SARS patients.
S1 contains the receptor-binding domain (RBD) that specifically binds to ACE2 receptors on host cells.
Variations in CoV Spike proteins influence receptor interactions and virus-cell membrane fusion responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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