Thermo Fisher Scientific HOMER3 Monoclonal Antibody (9G13)

Applications

Western Blot (WB)

• Tested Dilution: 0.1–0.5 µg/mL

Flow Cytometry (Flow)

• Tested Dilution: 1–3 µg/1×10⁶ cells

Product Specifications

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization.
The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors, and amyloid precursor proteins, and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation, and trafficking of amyloid beta peptides.
Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.