Thermo Fisher Scientific LILRB3 Monoclonal Antibody (08)
인간 LILRB3 단백질을 인식하는 Mouse IgG1 단일클론 항체입니다. Flow Cytometry에 적합하며, 비결합(Unconjugated) 형태로 제공됩니다. Protein A로 정제되었으며, 장기 보관 시 -20°C에서 냉동 보관이 권장됩니다.
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Applications
- Flow Cytometry (Flow): 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 08 |
| Immunogen | Recombinant Human LILRB3 Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866635 |
Target Information
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, located in the chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors, which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs).
The receptor is expressed on immune cells, where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits immune response stimulation. It is thought to regulate inflammatory responses and cytotoxicity, focusing the immune response and limiting autoreactivity. Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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