Thermo Fisher Scientific MICA Monoclonal Antibody (04)
인간 MICA 단백질을 인식하는 Mouse IgG1 단클론 항체입니다. Flow Cytometry와 ELISA에 사용 가능하며, 단백질 A로 정제된 액상 형태입니다. 단기 4°C, 장기 -20°C 보관이 권장됩니다. 연구용으로만 사용됩니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1:25–1:100
ELISA
- Tested Dilution: 1:1,000–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 04 |
| Immunogen | Recombinant Human MICA Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866638 |
Product Specific Information
This product can be used in direct ELISA.
Target Information
Major histocompatibility complex (MHC) class I proteins are ubiquitously expressed and mediate the recognition of intracellular antigens by cytotoxic T cells. A related family, termed the MHC class I chain-related (MIC) proteins, are recognized by NKG2D, a receptor on NK and T cells, and promote anti-tumor activity.
MICA, a member of the MIC family, is widely expressed on many tumors, and it is the MICA/NKG2D interaction that is thought to stimulate the anti-tumor reactivity by T lymphocytes. Both MICA and MICB mRNA are widely expressed in normal tissues, with MICA being present in virtually every tissue except the nervous system, suggesting that MIC protein expression may only be one component of the anti-tumor activity of the immune system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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