Thermo Fisher Scientific DENND4C Monoclonal Antibody (3E8), APC
DENND4C 단백질을 표적하는 APC 결합 단클론 항체로, Western blot, ICC/IF, IP 등 다양한 실험에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Protein G 정제, 보존제 무첨가. 연구용 전용 시약.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E8 |
| Immunogen | Full Length Human Recombinant DENND4C protein |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932414 |
Additional Formats
- FITC (MA5-45961)
- PerCP (MA5-45962)
- Custom conjugation available upon request
Product Specific Information
A 1:1,000 dilution of MA5-45960 was sufficient for detection of DENND4C in A549 and MEF cells by Western Blot analysis. Detects approximately 213 kDa.
Target Information
DENND4C is a guanine nucleotide exchange factor (GEF) activating RAB10. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. This process stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicle delivery to the plasma membrane in response to insulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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